I wonder if this can be used for other latent viruses that embed in cells like herpes and chickenpox/shingles.
stephen_g 14 hours ago [-]
Yeah, latent EBV would be great too since it seems to be one of the main causes of MS.
I believe this is already being researched with mRNA now, it would be amazing if it works out and we could treat all of these.
XorNot 15 hours ago [-]
That would be interesting because both of those have links to various late-life neurological conditions aa well.
Zigurd 19 hours ago [-]
MRNA therapies have such high potential, there really ought to be much more public education and outreach to prevent people falling down the quackery rabbit hole. I don't just say that to pile on to the quacks. It's so detrimental and costs so many lives that it's probably a target for influence by adversary nation actors.
dpe82 15 hours ago [-]
If we hadn't had a pandemic in which lots of people lost their collective minds and an irresponsible political machine that took advantage of that, mRNA would be pretty universally hailed as the miracle it is.
That aside, yes. Education is important. Sadly at least in the US some of the people who lost their minds are now in charge of such education.
chasil 15 hours ago [-]
This article asserts that white blood cells are the target, but we also know that (within the brain) astrocytes and [iirc] microglia can bear latent infection.
Is such a carrier capable of addressing latent reservoirs inside the blood-brain barrier? Can it cross the barrier, pervade the cerebrospinal fluid, then penetrate all infected cells?
White blood cells are a fantastic achievement, but far from the whole story.
18 hours ago [-]
dkkergoog 17 hours ago [-]
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yieldcrv 12 hours ago [-]
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joemazerino 10 hours ago [-]
Part of the pushback was the use of censorship apparatus during COVID. Science is supposed to be open to dispute, and silencing opposing opinions only adds to the conspiracy fuel.
the_real_cher 16 hours ago [-]
Lobotomy's were viewed to have so much high potential back in the day that they won the Nobel prize.
In true scientific fashion both sides would ideally just stick with the facts.
hobs 14 hours ago [-]
There's no "both sides" in science.
more_corn 10 hours ago [-]
I mean, there is the side that is backed by evidence and the one that is not.
That’s two sides. I just don’t feel inclined to listen to the side that is not.
the_real_cher 2 hours ago [-]
I guess the side that give the Nobel prize to lobotomies wasnt backed by evidence?
Or were they backed by evidence?
And then stronger more compelling evidence came out later against?
Thats kind of how science works, its a process of discovery not a set in stone right/wrong.
Things arent as reductionist as you claim, it does people good when they open their world up to that fact.
6 hours ago [-]
therein 19 hours ago [-]
[flagged]
foota 19 hours ago [-]
Unsubstantiated skepticism is unhealthy.
therein 19 hours ago [-]
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greglansky 19 hours ago [-]
Did you survive from childhood to adulthood, even having been sick when you were young? If the answer is "yes", the trust is substantiated.
therein 18 hours ago [-]
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dyauspitr 18 hours ago [-]
It doesn’t seem like a comeback, more a validation of the process we have in place to greenlight medical therapies.
leereeves 15 hours ago [-]
My grandmother died because of an FDA approved therapy that was later pulled from the market. One of many [1].
Given that experience, I think the process we have in place to greenlight medical therapies is not perfect, and I don't think it's unreasonable to be more cautious than the FDA is.
Yes, there are other cases too like thalidomide. Edge cases or misses don’t mean that you throw the baby out with the bathwater. What’s the alternative? Let skeptical people keep effective treatments from the vast majority of the population?
leereeves 13 hours ago [-]
It seemed to me like most of the opposition was to the mandate rather than to letting people take the vaccine if they chose to.
dyauspitr 10 hours ago [-]
The way vaccines work is you can never really eradicate things if everyone doesn’t take it. We would still have smallpox floating around if the vaccination drive wasn’t mandatory.
Additionally the GP here is advocating for restricting mRNA research in general which seems to be a general theme with the post truth folks.
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Rendered at 14:03:25 GMT+0000 (Coordinated Universal Time) with Vercel.
I believe this is already being researched with mRNA now, it would be amazing if it works out and we could treat all of these.
That aside, yes. Education is important. Sadly at least in the US some of the people who lost their minds are now in charge of such education.
Is such a carrier capable of addressing latent reservoirs inside the blood-brain barrier? Can it cross the barrier, pervade the cerebrospinal fluid, then penetrate all infected cells?
White blood cells are a fantastic achievement, but far from the whole story.
In true scientific fashion both sides would ideally just stick with the facts.
Or were they backed by evidence?
And then stronger more compelling evidence came out later against?
Thats kind of how science works, its a process of discovery not a set in stone right/wrong.
Things arent as reductionist as you claim, it does people good when they open their world up to that fact.
Given that experience, I think the process we have in place to greenlight medical therapies is not perfect, and I don't think it's unreasonable to be more cautious than the FDA is.
Especially when the treatment is mandatory.
1: https://en.wikipedia.org/wiki/List_of_withdrawn_drugs
Additionally the GP here is advocating for restricting mRNA research in general which seems to be a general theme with the post truth folks.